The visualization of structures of macromolecules at the  atomic level
   is  both  computationally demanding and human labor intensive.   The overall
   procedure will be described, including definition of common bottlenecks and
   applications of some principles from computer science to address them.  Many
   challenges remain, and collaborations with the applied  math, optimization,
   high-performance  computing, graphics, and AI communities would be very wel-
   come.