Oil refineries provide the lifeblood for global economic health, and disruptions to their operations have major worldwide impact. For almost a decade, Honeywell's Automated Reasoning Group has been working together with over a dozen major petrochemical companies to move their industry into the next generation of sophisticated software control systems. One of the most ambitious and innovative aspects of this program has been the application of AI techniques to control these complex plants during normal, and especially abnormal situations. We are developing a large-scale intelligent refinery control system to either assist human operators, or automate certain plant procedures directly, depending on what each situation warrants. Based on reactive and procedural approaches to intelligent behavior, the Abnormal Event Guidance and Information System (AEGIS) will interact with multiple users and thousands of refinery components to diagnose and compensate for unanticipated plant disruptions. Adjusting the autonomy of AEGIS's behavior to intelligently adapt to each individual situation is a key requirement for success in the dynamic, highly-unpredictable refinery environment. In this talk I will discuss our technical approach to the goal-setting, planning, and plan execution components of AEGIS, and the adjustable autonomy features they support. Then, to complement this depth-first exploration of a single project, I will briefly provide a breadth-first overview of several other projects currently underway in our research group.